tert-Butyl esters are commonly used as protecting group of carboxylic acids in multi-step synthesis, especially with amino acids, peptides and natural products. [1] The importance of this relatively hindered protecting group is well established.
tert-Butyl Nitrite-Mediated Synthesis of N-Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
An efficient synthesis of ฮฑ-deuterated carboxylic acids
Organic Syntheses Procedure
Tert-Butylation - an overview
Efficient and Controllably Selective Preparation of Esters Using Uronium-Based Coupling Agents
An efficient synthesis of ฮฑ-deuterated carboxylic acids
An efficient synthesis of N-tert-butyl amides by the reaction of tert-butyl benzoate with nitriles catalyzed by Zn(ClO4)2ยท6H2O
Approaches for the Synthesis of Functionalized Cryptophycins
Enantioselective Total Syntheses of Cyathane Diterpenoids - Nakada - 2014 - The Chemical Record - Wiley Online Library
Uses for Akanocure Stereotetrad Lactones 5a: Full Lactone Reductions
Full article: Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis
Full article: Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis
ZnEt2 as a Precatalyst for the Addition of Alcohols to Carbodiimides
Enantioselective Total Syntheses of Cyathane Diterpenoids - Nakada - 2014 - The Chemical Record - Wiley Online Library